Continuing the World Antimicrobial Awareness Week (WAAW) momentum, our AMR Frontline Workshop made its next stop in the cultural capital of Karnataka—Mysore. Hosted by Mysore Medical College on November 27, 2024, the workshop aimed to educate interns and postgraduate students through insightful talks and interactive activities. Dr. Mansi Malik, Research Scientist at TIGS, shared her lab’s pioneering work in developing indigenous RT-PCR assays for AMR pathogen detection, emphasizing the importance of the “Three As”—Assay Development, Accurate Diagnosis, and Affordable Price. Dr. Sukanya R, Clinical Microbiologist and Infection Prevention Practitioner at Motherhood Hospitals, stressed the need to “Know your bug first, then your drug,” cautioning against the overuse of broad-spectrum antibiotics with striking phrases like “Not every ICU patient needs KingKongopenem” and “The winning horse can be changed – deescalate when needed.” Dr. Akshay HM, Head of Critical Care at JSS Medical College, discussed the challenges posed by ESKAPE pathogens, the rise in ICU fungal infections, and the critical role of proper antibiotic dosage and administration. Adding a fun twist to the learning, participants engaged in a Kahoot quiz on antibiotic PK/PD, Taboo: AMR Edition, and Jeopardy Jamboree, making the workshop both educational and highly interactive.